Description
| 抗体名: | NAT2 Antibody (PACO10740) |
| 抗体コード: | PACO10740 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human NAT2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | N-acetyltransferase 2 (arylamine N-acetyltransferase);NAT2;AAC2;PNAT ; |
| UniProt Protein Function: | NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family. |
| UniProt Protein Details: | Protein type:Acetyltransferase; EC 2.3.1.5; Secondary Metabolites Metabolism - caffeine; Translation; Xenobiotic Metabolism - drug metabolism - other enzymes Chromosomal Location of Human Ortholog: 8p22 Cellular Component: cytosol Molecular Function:arylamine N-acetyltransferase activity; protein binding Biological Process: xenobiotic metabolic process Disease: Acetylation, Slow |
| NCBI Summary: | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008] |
| UniProt Code: | P11245 |
| NCBI GenInfo Identifier: | 114238 |
| NCBI Gene ID: | 10 |
| NCBI Accession: | P11245.1 |
| UniProt Secondary Accession: | P11245,O43637, O60654, O60655, Q13146, Q16697, Q2MLE4 Q2MLF5, Q2MLG8, Q2MLJ6, Q2MLK4, Q2MLK6, |
| UniProt Related Accession: | P11245 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | Arylamine N-acetyltransferase 2 |
| NCBI Synonym Full Names: | N-acetyltransferase 2 |
| NCBI Official Symbol: | NAT2 |
| NCBI Official Synonym Symbols: | AAC2; PNAT; NAT-2 |
| NCBI Protein Information: | arylamine N-acetyltransferase 2 |
| UniProt Protein Name: | Arylamine N-acetyltransferase 2 |
| UniProt Synonym Protein Names: | Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT |
| Protein Family: | N-terminal acetyltransferase |
| UniProt Gene Name: | NAT2 |
