Description
| 抗体名: | MYL2 Antibody (PACO10686) |
| 抗体コード: | PACO10686 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat, Zebrafish |
| 免疫原: | Human MYL2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | myosin, light chain 2, regulatory, cardiac, slow;MYL2;CMH10;DKFZp779C0562;MLC2 ;MLC-2v; MLC-2 |
| UniProt Protein Function: | MRLC2V: myosin regulatory light chain 2, ventricular/cardiac muscle isoform. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. |
| UniProt Protein Details: | Protein type:Contractile Chromosomal Location of Human Ortholog: 12q24.11 Cellular Component: sarcomere; cytoskeleton; myofibril; cytosol; myosin complex; A band; actin cytoskeleton Molecular Function:actin monomer binding; protein binding; structural constituent of muscle; calcium ion binding; myosin heavy chain binding Biological Process: muscle cell fate specification; heart contraction; regulation of striated muscle contraction; ventricular cardiac muscle morphogenesis; cardiac myofibril assembly; negative regulation of cell growth; muscle fiber development; muscle filament sliding; cardiac muscle contraction; post-embryonic development Disease: Cardiomyopathy, Familial Hypertrophic, 10 |
| NCBI Summary: | Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P10916 |
| NCBI GenInfo Identifier: | 6166556 |
| NCBI Gene ID: | 4633 |
| NCBI Accession: | P10916.3 |
| UniProt Secondary Accession: | P10916,Q16123, |
| UniProt Related Accession: | P10916 |
| Molecular Weight: | 166 |
| NCBI Full Name: | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform |
| NCBI Synonym Full Names: | myosin, light chain 2, regulatory, cardiac, slow |
| NCBI Official Symbol: | MYL2 |
| NCBI Official Synonym Symbols: | MLC2; CMH10 |
| NCBI Protein Information: | myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v; RLC of myosin; myosin light chain 2; regulatory light chain of myosin; cardiac ventricular myosin light chain 2; slow cardiac myosin regulatory light chain 2; myosin, light polypeptide 2, regulatory, cardiac, slow |
| UniProt Protein Name: | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform |
| Protein Family: | Myosin regulatory |
| UniProt Gene Name: | MYL2 |
| UniProt Entry Name: | MLRV_HUMAN |
