| UniProt Protein Function: | MTP18: Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis. Belongs to the MTFP1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 22q Cellular Component: mitochondrial inner membrane; integral to membrane Biological Process: mitochondrial fission; apoptosis |
| NCBI Summary: | MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UDX5 |
| NCBI GenInfo Identifier: | 52783151 |
| NCBI Gene ID: | 51537 |
| NCBI Accession: | Q9UDX5.1 |
| UniProt Secondary Accession: | Q9UDX5,Q9H3K1, Q9P0N6, A6NFQ5, |
| UniProt Related Accession: | Q9UDX5 |
| Molecular Weight: | 166 |
| NCBI Full Name: | Mitochondrial fission process protein 1 |
| NCBI Synonym Full Names: | mitochondrial fission process 1 |
| NCBI Official Symbol: | MTFP1 |
| NCBI Official Synonym Symbols: | MTP18; HSPC242 |
| NCBI Protein Information: | mitochondrial fission process protein 1; mitochondrial 18 kDa protein; mitochondrial protein 18 kDa; mitochondrial fission protein MTP18 |
| UniProt Protein Name: | Mitochondrial fission process protein 1 |
| UniProt Synonym Protein Names: | Mitochondrial 18 kDa protein; MTP18 |
| Protein Family: | Mitochondrial fission process protein |
| UniProt Gene Name: | MTFP1 |
| UniProt Entry Name: | MTFP1_HUMAN |
