Description
| 抗体名: | MT-ND3 Antibody (PACO20050) |
| 抗体コード: | PACO20050 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| 反応性: | Human |
| 免疫原: | Synthetic peptide of human MT-ND3 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20050(MT-ND3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20050(MT-ND3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| バックグラウンド: | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease. |
| シノニム: | mitochondrially encoded NADH dehydrogenase 3 |
| UniProt Protein Function: | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| UniProt Code: | P03897 |
| NCBI GenInfo Identifier: | 128710 |
| NCBI Gene ID: | 4537 |
| NCBI Accession: | P03897.1 |
| UniProt Related Accession: | P03897 |
| Molecular Weight: | 13,186 Da |
| NCBI Full Name: | NADH-ubiquinone oxidoreductase chain 3 |
| NCBI Synonym Full Names: | mitochondrially encoded NADH dehydrogenase 3 |
| NCBI Official Symbol: | MT-ND3 |
| NCBI Official Synonym Symbols: | MTND3; ND3 |
| NCBI Protein Information: | NADH dehydrogenase, subunit 3 (complex I) |
| UniProt Protein Name: | NADH-ubiquinone oxidoreductase chain 3 |
| UniProt Synonym Protein Names: | NADH dehydrogenase subunit 3 |
| UniProt Gene Name: | MT-ND3 |
| Antibodies |
| Anti-MT-ND3 Antibody (CAB17969) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
