Description
| 抗体名: | MRPL18 Antibody (PACO22088) |
| 抗体コード: | PACO22088 |
| サイズ: | 100ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from internal of human MRPL18. |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HT-29 cells, using MRPL18 antibody. |
| バックグラウンド: | Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. |
| シノニム: | 39S ribosomal protein L18; mitochondrial; L18mt; mitochondrial ribosomal protein L18; MRP-L18 |
| UniProt Protein Function: | MRPL18: Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA. Belongs to the ribosomal protein L18P family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Ribosomal; Translation Chromosomal Location of Human Ortholog: 6q25.3 Cellular Component: extracellular space; mitochondrial inner membrane; mitochondrial ribosome; mitochondrion Molecular Function:5S rRNA binding; structural constituent of ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis; translation |
| NCBI Summary: | This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q9H0U6 |
| NCBI GenInfo Identifier: | 41017797 |
| NCBI Gene ID: | 29074 |
| NCBI Accession: | Q9H0U6.1 |
| UniProt Secondary Accession: | Q9H0U6,Q5TAP9, Q9NZW8, |
| UniProt Related Accession: | Q9H0U6 |
| Molecular Weight: | 20,577 Da |
| NCBI Full Name: | 39S ribosomal protein L18, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L18 |
| NCBI Official Symbol: | MRPL18 |
| NCBI Official Synonym Symbols: | L18mt; HSPC071; MRP-L18 |
| NCBI Protein Information: | 39S ribosomal protein L18, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L18, mitochondrial |
| UniProt Gene Name: | MRPL18 |
| UniProt Entry Name: | RM18_HUMAN |
