Description
| Product Name: | Mouse S100A6 Recombinant Protein |
| Product Code: | RPPB4744 |
| Size: | 5µg |
| Species: | Mouse |
| Target: | S100A6 |
| Synonyms: | Protein S100-A6, S100 calcium-binding protein A6, Calcyclin, Prolactin receptor-associated protein, 5B10, S100a6, Cacy, 2A9, PRA. |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | The protein was lyophilized from a concentrated solution (1mg/ml) containing no additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Mouse S100A6 in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Mouse S100A6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse S100A6 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21.S100A6 may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of the S100A6 gene are implicated in melanoma.
S100A6 also called Calcyclin has been purified by HPLC (see Kuznicki et al. (1989) Biochem. J. 263: 951-956).
| UniProt Protein Function: | S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3 F1|3 39.35 cM Cellular Component: cytoplasm; cytosol; extrinsic component of cytoplasmic side of plasma membrane; membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle Molecular Function:calcium ion binding; calcium-dependent protein binding; ion transmembrane transporter activity; metal ion binding; protein binding; protein homodimerization activity; tropomyosin binding; zinc ion binding |
| UniProt Code: | P14069 |
| NCBI GenInfo Identifier: | 6755392 |
| NCBI Gene ID: | 20200 |
| NCBI Accession: | NP_035443.1 |
| UniProt Related Accession: | P14069 |
| Molecular Weight: | 10,051 Da |
| NCBI Full Name: | protein S100-A6 |
| NCBI Synonym Full Names: | S100 calcium binding protein A6 (calcyclin) |
| NCBI Official Symbol: | S100a6�� |
| NCBI Official Synonym Symbols: | 2A9; PRA; 5B10; Cacy; CALCYCLIN�� |
| NCBI Protein Information: | protein S100-A6 |
| UniProt Protein Name: | Protein S100-A6 |
| UniProt Synonym Protein Names: | 5B10; Calcyclin; Prolactin receptor-associated protein; S100 calcium-binding protein A6 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100a6�� |
