Description
| Product Name: | Mouse IMPAD1 Bioactive Recombinant Protein |
| Product Code: | RPPB3746 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | IMPAD1 Bioactive |
| Synonyms: | Inositol monophosphatase 3, IMP 3, IMPase 3, Golgi 3-primephosphoadenosine 5-prime phosphate 3-prime phosphatase, Golgi-resident PAPphosphatase, gPAPP, Inositol monophosphatase domain-containing protein 1, Inositol-1(or4)-monophosphatase 3, Myo-inositol monophosphatase A3. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | IMPAD1 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPGRFSLFG LGSEPAAGEAEVASDGGTVD LREMLAVAVL AAERGGDEVR RVRESNVLHE KSKGKTREGA DDKMTSGDVL SNRKMFYLLK TAFPNVQINTEEHVDASDKE VIVWNRKIPE DILKEIAAPK EVPAESVTVW IDPLDATQEY TEDLRKYVTT MVCVAVNGKPVLGVIHKPFSEYTAWAMVDG GSNVKARSSYNEKTPKIIVS RSHAGMVKQV ALQTFGNQTS IIPAGGAGYK VLALLDVPDM TQEKADLYIH VTYIKKWDIC AGNAILKALGGHMTTLNGEE ISYTGSDGIE GGLLASIRMN HQALVRKLPD LEKSGHHHHH HH |
| Biological Activity: | Specificactivity is > 5,000 pmol/min/ug and is defined as the amount of enzyme thathydrolyze Adenosine 3, 5-diphosphate per minute at pH 7.5 at 25C. |
| UniProt Code: | Q80V26 |
Inositol monophosphatase 3 (IMPAD1) belongs to the inositol monophosphatase family. IMPAD1 is restricted to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). IMPAD1 gene mutations cause the GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of the IMPAD1 gene is located on the long arm of chromosome 1.
IMPAD1 Mouse Recombinant produced in Sf9 Baculoviruscells is a single, glycosylated polypeptide chain containing 332 amino acids (34-356a.a.)and having a molecular mass of 36.2kDa. (Molecular size on SDS-PAGE will appearat approximately 28-40kDa).�IMPAD1 is expressed with a6 amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.
