Description
| 抗体名: | MOK Antibody |
| 抗体コード: | PACO01404 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human RAGE. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | MOK; RAGE; RAGE1; MAPK/MAK/MRK overlapping kinase; MOK protein kinase; Renal tumor antigen 1; RAGE-1 |
| UniProt Protein Function: | MOK: a CMGC protein kinase of the RCK family. Possesses a Thr-Glu-Tyr motif in the activation loop domain, as do classical MAP kinases. Associates with and is apparently stabilized by HSP90. |
| UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, CMGC; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; RCK family Chromosomal Location of Human Ortholog: 14q32 Cellular Component: cytoplasm Molecular Function:protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; ATP binding; protein kinase activity Biological Process: regulation of cell cycle; signal transduction; protein amino acid phosphorylation |
| NCBI Summary: | This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q9UQ07 |
| NCBI GenInfo Identifier: | 41017258 |
| NCBI Gene ID: | 5891 |
| NCBI Accession: | Q9UQ07.1 |
| UniProt Secondary Accession: | Q9UQ07,Q92790, Q93067, B2R6Z4, B7Z7P6, E7ER76, E7ERR8 |
| UniProt Related Accession: | Q9UQ07 |
| Molecular Weight: | 419 |
| NCBI Full Name: | MAPK/MAK/MRK overlapping kinase |
| NCBI Synonym Full Names: | MOK protein kinase |
| NCBI Official Symbol: | MOK |
| NCBI Official Synonym Symbols: | RAGE; RAGE1; STK30; RAGE-1 |
| NCBI Protein Information: | MAPK/MAK/MRK overlapping kinase; renal tumor antigen 1; renal cell carcinoma antigen |
| UniProt Protein Name: | MAPK/MAK/MRK overlapping kinase |
| UniProt Synonym Protein Names: | MOK protein kinase; Renal tumor antigen 1; RAGE-1 |
| Protein Family: | MAPK/MAK/MRK overlapping kinase |
| UniProt Gene Name: | MOK |
| UniProt Entry Name: | MOK_HUMAN |
