Description
| 抗体名: | ME2 Antibody, HRP conjugated (PACO46019) |
| 抗体コード: | PACO46019 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human NAD-dependent malic enzyme, mitochondrial protein (296-424AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | intracellular membrane-bounded organelle, mitochondrion, electron carrier activity, malate dehydrogenase (decarboxylating) (NAD+) activity, malic enzyme activity, regulation of NADP metabolic process |
| シノニム: | NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2), ME2 |
| UniProt Protein Function: | ME2: a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - pyruvate; Oxidoreductase; Mitochondrial; EC 1.1.1.38 Chromosomal Location of Human Ortholog: 18q21 Cellular Component: intracellular membrane-bound organelle; mitochondrion Molecular Function:electron carrier activity; malic enzyme activity Disease: Epilepsy, Idiopathic Generalized; Opioid Dependence, Susceptibility To, 1 |
| NCBI Summary: | This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | P23368 |
| NCBI GenInfo Identifier: | 126733 |
| NCBI Gene ID: | 4200 |
| NCBI Accession: | P23368.1 |
| UniProt Secondary Accession: | P23368,Q9BWL6, Q9BYG1, Q9H4B2, B2R8J2, |
| UniProt Related Accession: | P23368 |
| Molecular Weight: | 53,586 Da |
| NCBI Full Name: | NAD-dependent malic enzyme, mitochondrial |
| NCBI Synonym Full Names: | malic enzyme 2 |
| NCBI Official Symbol: | ME2 |
| NCBI Official Synonym Symbols: | ODS1 |
| NCBI Protein Information: | NAD-dependent malic enzyme, mitochondrial |
| UniProt Protein Name: | NAD-dependent malic enzyme, mitochondrial |
| UniProt Synonym Protein Names: | Malic enzyme 2 |
| UniProt Gene Name: | ME2 |
| UniProt Entry Name: | MAOM_HUMAN |
