Description
| 抗体名: | MCMBP Antibody (PACO08070) |
| 抗体コード: | PACO08070 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human C10orf119 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | chromosome 10 open reading frame 119;C10orf119;FLJ13081;FLJ36756;MCM-BP;MCMBP ; |
| UniProt Protein Function: | MCMBP: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. Belongs to the MCMBP family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 10q26.11 Cellular Component: nucleoplasm; MCM complex; cytoplasm; plasma membrane; nucleus Molecular Function:protein binding; chromatin binding Biological Process: mitosis; cell division; sister chromatid cohesion; DNA-dependent DNA replication |
| NCBI Summary: | This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q9BTE3 |
| NCBI GenInfo Identifier: | 71153001 |
| NCBI Gene ID: | 79892 |
| NCBI Accession: | Q9BTE3.2 |
| UniProt Related Accession: | Q9BTE3 |
| Molecular Weight: | 52kDa; 72kDa |
| NCBI Full Name: | Mini-chromosome maintenance complex-binding protein |
| NCBI Synonym Full Names: | minichromosome maintenance complex binding protein |
| NCBI Official Symbol: | MCMBP |
| NCBI Official Synonym Symbols: | MCM-BP; C10orf119 |
| NCBI Protein Information: | mini-chromosome maintenance complex-binding protein |
| UniProt Protein Name: | Mini-chromosome maintenance complex-binding protein |
| Protein Family: | Mini-chromosome maintenance complex-binding protein |
| UniProt Gene Name: | MCMBP |
| UniProt Entry Name: | MCMBP_HUMAN |
