Description
| 抗体名: | MCIDAS Antibody, FITC conjugated (PACO46468) |
| 抗体コード: | PACO46468 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Multicilin protein (3-110AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. |
| シノニム: | Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas), MCIDAS, IDAS MCI MCIN |
| UniProt Protein Function: | MCIDAS: Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Belongs to the geminin family. Homodimer. Interacts with GMNN; targets GMNN to the nucleus, prevents GMNN interaction with CDT1 and competes with IDAS homodimerizationChromosomal Location of Human Ortholog: 5q11.2Cellular Component: nucleolus; nucleusMolecular Function: identical protein binding; protein bindingBiological Process: cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of mitotic cell cycle |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | D6RGH6 |
| NCBI GenInfo Identifier: | 342164929 |
| NCBI Gene ID: | 345643 |
| NCBI Accession: | D6RGH6.1 |
| UniProt Secondary Accession: | D6RGH6,C9JGY3, D6R920, F8KGQ8 |
| UniProt Related Accession: | D6RGH6 |
| Molecular Weight: | 41,720 Da |
| NCBI Full Name: | Multicilin |
| NCBI Synonym Full Names: | multiciliate differentiation and DNA synthesis associated cell cycle protein |
| NCBI Official Symbol: | MCIDAS |
| NCBI Official Synonym Symbols: | MCI; IDAS; MCIN |
| NCBI Protein Information: | multicilin |
| UniProt Protein Name: | Multicilin |
| UniProt Synonym Protein Names: | Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Protein Idas |
| Protein Family: | Multicilin |
| UniProt Gene Name: | MCIDAS |
| UniProt Entry Name: | MCIN_HUMAN |
