Description
| 抗体名: | MAP2 Antibody |
| 抗体コード: | PACO04278 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the N-terminal region of human MAP-2. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | MAP2; Microtubule-associated protein 2; MAP-2 |
| UniProt Protein Function: | MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q34-q35 Cellular Component: cell soma; cytoplasm; dendritic shaft; microtubule; microtubule associated complex; neuron projection; nucleolus Molecular Function:calmodulin binding; microtubule binding; protein binding; structural molecule activity Biological Process: axonogenesis; central nervous system neuron development; dendrite morphogenesis; microtubule bundle formation; microtubule cytoskeleton organization and biogenesis; neurite development |
| NCBI Summary: | This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010] |
| UniProt Code: | P11137 |
| NCBI GenInfo Identifier: | 215274255 |
| NCBI Gene ID: | 4133 |
| NCBI Accession: | P11137.4 |
| UniProt Secondary Accession: | P11137,Q17S04, Q8IUX2, Q99975, Q99976, |
| UniProt Related Accession: | P11137 |
| Molecular Weight: | |
| NCBI Full Name: | Microtubule-associated protein 2 |
| NCBI Synonym Full Names: | microtubule associated protein 2 |
| NCBI Official Symbol: | MAP2 |
| NCBI Official Synonym Symbols: | MAP2A; MAP2B; MAP2C |
| NCBI Protein Information: | microtubule-associated protein 2 |
| UniProt Protein Name: | Microtubule-associated protein 2 |
| Protein Family: | Microtubule-associated protein |
| UniProt Gene Name: | MAP2 |
| UniProt Entry Name: | MTAP2_HUMAN |
