Description
| 抗体名: | MAK Antibody (PACO10350) |
| 抗体コード: | PACO10350 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human MAK |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | male germ cell-associated kinase;MAK;dJ417M14.2 ; |
| UniProt Protein Function: | MAK: a protein kinase of the RCK family of kinases. It is expressed at high levels in the testis (primarily in germ cells), and in developing sensory epithelia. Localizes to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. |
| UniProt Protein Details: | Protein type:Protein kinase, CMGC; EC 2.7.11.22; Nuclear receptor co-regulator; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; RCK family Chromosomal Location of Human Ortholog: 6p24 Cellular Component: centrosome; midbody; nucleus; photoreceptor inner segment; photoreceptor outer segment Molecular Function:protein binding; transcription coactivator activity Biological Process: photoreceptor cell maintenance; protein amino acid autophosphorylation; protein amino acid phosphorylation Disease: Retinitis Pigmentosa 62 |
| NCBI Summary: | The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Code: | P20794 |
| NCBI GenInfo Identifier: | 13432166 |
| NCBI Gene ID: | 4117 |
| NCBI Accession: | P20794.2 |
| UniProt Secondary Accession: | P20794,Q547D0, Q9NUH7, F1T0K6, G1FL29, |
| UniProt Related Accession: | P20794 |
| Molecular Weight: | 66,345 Da |
| NCBI Full Name: | Serine/threonine-protein kinase MAK |
| NCBI Synonym Full Names: | male germ cell associated kinase |
| NCBI Official Symbol: | MAK |
| NCBI Official Synonym Symbols: | RP62 |
| NCBI Protein Information: | serine/threonine-protein kinase MAK |
| UniProt Protein Name: | Serine/threonine-protein kinase MAK |
| UniProt Synonym Protein Names: | Male germ cell-associated kinase |
| Protein Family: | Makatoxin |
| UniProt Gene Name: | MAK |
| UniProt Entry Name: | MAK_HUMAN |
