Description
| 抗体名: | LPCAT1 Antibody (PACO10279) |
| 抗体コード: | PACO10279 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human LPCAT1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | lysophosphatidylcholine acyltransferase 1;LPCAT1;AYTL2;FLJ12443;FLJ41609;PFAAP3;lpcat ; |
| UniProt Protein Function: | LPCAT1: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.67; Acetyltransferase; Membrane protein, integral; EC 2.3.1.23; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane; lipid particle Molecular Function:1-alkylglycerophosphocholine O-acetyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-alkenylglycerophosphocholine O-acyltransferase activity; 1-alkylglycerophosphocholine O-acyltransferase activity; calcium ion binding Biological Process: retina development in camera-type eye; phospholipid metabolic process; glycerophospholipid biosynthetic process; positive regulation of protein catabolic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; surfactant homeostasis; phospholipid biosynthetic process |
| NCBI Summary: | Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008] |
| UniProt Code: | Q8NF37 |
| NCBI GenInfo Identifier: | 110815902 |
| NCBI Gene ID: | 79888 |
| NCBI Accession: | Q8NF37.2 |
| UniProt Secondary Accession: | Q8NF37,Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6, |
| UniProt Related Accession: | Q8NF37 |
| Molecular Weight: | Calculated MW: 59kDaObserved MW:59kDa |
| NCBI Full Name: | Lysophosphatidylcholine acyltransferase 1 |
| NCBI Synonym Full Names: | lysophosphatidylcholine acyltransferase 1 |
| NCBI Official Symbol: | LPCAT1 |
| NCBI Official Synonym Symbols: | AYTL2; lpcat; PFAAP3 |
| NCBI Protein Information: | lysophosphatidylcholine acyltransferase 1; LPCAT-1; lysoPAFAT; LPC acyltransferase 1; acyltransferase like 2; acyltransferase-like 2; lysoPC acyltransferase 1; lyso-PAF acetyltransferase; regulated by phosphonoformate; acetyl-CoA:lyso-PAF acetyltransferase; phosphonoformate immuno-associated protein 3; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 1; acetyl-CoA:lyso-platelet-activating factor acetyltransferase |
| UniProt Protein Name: | Lysophosphatidylcholine acyltransferase 1 |
| UniProt Synonym Protein Names: | 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase (EC:2.3.1.67); Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; Acyltransferase-like 2; Phosphonoformate immuno-associated protein 3 |
| Protein Family: | Lysophosphatidylcholine acyltransferase |
| UniProt Gene Name: | LPCAT1 |
| UniProt Entry Name: | PCAT1_HUMAN |
