Description
| 抗体名: | LPAR2 Antibody (PACO05706) |
| 抗体コード: | PACO05706 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000, IF:1:200-1:1000 |
| 反応性: | Human, Mouse, Monkey |
| 免疫原: | Synthesized peptide derived from the C-terminal region of human EDG-4. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | LPAR2; EDG4; LPA2; Lysophosphatidic acid receptor 2; LPA receptor 2; LPA-2; Lysophosphatidic acid receptor Edg-4 |
| UniProt Protein Function: | EDG4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 19p12 Cellular Component: cell surface; endocytic vesicle; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; lipid binding; protein binding Biological Process: elevation of cytosolic calcium ion concentration; phospholipase C activation |
| NCBI Summary: | This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HBW0 |
| NCBI GenInfo Identifier: | 26393399 |
| NCBI Gene ID: | 9170 |
| NCBI Accession: | Q9HBW0.2 |
| UniProt Secondary Accession: | Q9HBW0,O00543, O43431, |
| UniProt Related Accession: | Q9HBW0 |
| Molecular Weight: | 39,084 Da |
| NCBI Full Name: | Lysophosphatidic acid receptor 2 |
| NCBI Synonym Full Names: | lysophosphatidic acid receptor 2 |
| NCBI Official Symbol: | LPAR2 |
| NCBI Official Synonym Symbols: | EDG4; LPA2; EDG-4; LPA-2 |
| NCBI Protein Information: | lysophosphatidic acid receptor 2 |
| UniProt Protein Name: | Lysophosphatidic acid receptor 2 |
| UniProt Synonym Protein Names: | Lysophosphatidic acid receptor Edg-4 |
| Protein Family: | Lysophosphatidic acid receptor |
| UniProt Gene Name: | LPAR2 |
| UniProt Entry Name: | LPAR2_HUMAN |
