Description
| 抗体名: | LINGO1 Antibody (PACO10263) |
| 抗体コード: | PACO10263 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human LINGO1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | leucine rich repeat and Ig domain containing 1;LINGO1;FLJ14594;LERN1;LRRN6A;MGC17422;UNQ201 ; |
| UniProt Protein Function: | LINGO1: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 15q24.3 Cellular Component: plasma membrane Molecular Function:epidermal growth factor receptor binding; protein binding Biological Process: axonogenesis; negative regulation of axonogenesis; signal transduction |
| UniProt Code: | Q96FE5 |
| NCBI GenInfo Identifier: | 50263044 |
| NCBI Gene ID: | 84894 |
| NCBI Accession: | NP_116197 |
| UniProt Secondary Accession: | Q96FE5,Q6NUK3, Q6UXM3, Q6VVG0, Q6VVG1, Q6VVG2, Q8N3K5 Q96K52, D3DW80, |
| UniProt Related Accession: | Q96FE5 |
| Molecular Weight: | 15.1kDa (133aa) |
| NCBI Full Name: | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform a |
| NCBI Synonym Full Names: | leucine rich repeat and Ig domain containing 1 |
| NCBI Official Symbol: | LINGO1 |
| NCBI Official Synonym Symbols: | LERN1; LRRN6A; UNQ201 |
| NCBI Protein Information: | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
| UniProt Protein Name: | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 |
| UniProt Synonym Protein Names: | Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A |
| UniProt Gene Name: | LINGO1 |
| UniProt Entry Name: | LIGO1_HUMAN |
