Description
| 抗体名: | LHX1 Antibody |
| 抗体コード: | PACO04235 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human LHX1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | LHX1; LIM-1; LIM1; LIM/homeobox protein Lhx1; LIM homeobox protein 1; Homeobox protein Lim-1; hLim-1 |
| UniProt Protein Function: | LHX1: Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis. |
| UniProt Protein Details: | Protein type:Transcription factor; Cell development/differentiation Chromosomal Location of Human Ortholog: 17q12 Cellular Component: protein complex; nucleus Molecular Function:zinc ion binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; motor axon guidance; uterus development; forebrain regionalization; embryonic pattern specification; pronephros development; post-embryonic development; anterior/posterior pattern formation; cell-cell signaling; ectoderm formation; ureteric bud development; anatomical structure formation; cerebellum development; kidney development; fallopian tube development; cervix development; nervous system development; anatomical structure morphogenesis; vagina development; ventral spinal cord development; gastrulation with mouth forming second; embryonic viscerocranium morphogenesis; somite rostral/caudal axis specification; pattern specification process; Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; organ morphogenesis; telencephalon development; positive regulation of embryonic development; dorsal/ventral pattern formation; regulation of gene expression; endoderm formation; ureteric bud branching; embryonic retina morphogenesis in camera-type eye; cerebellar Purkinje cell differentiation; spinal cord association neuron differentiation; negative regulation of transcription, DNA-dependent; urogenital system development; anterior/posterior axis specification |
| NCBI Summary: | This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010] |
| UniProt Code: | P48742 |
| NCBI GenInfo Identifier: | 30410785 |
| NCBI Gene ID: | 3975 |
| NCBI Accession: | NP_005559 |
| UniProt Related Accession: | P48742 |
| Molecular Weight: | 45kDa |
| NCBI Full Name: | LIM/homeobox protein Lhx1 |
| NCBI Synonym Full Names: | LIM homeobox 1 |
| NCBI Official Symbol: | LHX1 |
| NCBI Official Synonym Symbols: | LIM1; LIM-1 |
| NCBI Protein Information: | LIM/homeobox protein Lhx1 |
| UniProt Protein Name: | LIM/homeobox protein Lhx1 |
| UniProt Synonym Protein Names: | Homeobox protein Lim-1 |
| UniProt Gene Name: | LHX1 |
| UniProt Entry Name: | LHX1_HUMAN |
