Description
| 抗体名: | L3MBTL2 Antibody (PACO52602) |
| 抗体コード: | PACO52602 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:200-1:2000, IF:1:50-1:200 |
| 反応性: | Human, Rat |
| 免疫原: | Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein (1-230AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO52602 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Western Blot. Positive WB detected in: K562 whole cell lysate, Rat heart tissue. All lanes: L3MBTL2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 80, 70 kDa. Observed band size: 70 kDa. |
| バックグラウンド: | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. |
| シノニム: | Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2), L3MBTL2 |
| UniProt Protein Function: | L3MBTL2: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Histone-binding Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: nucleoplasm; nucleus Molecular Function:histone binding; methylated histone residue binding; protein binding Biological Process: protein sumoylation |
| UniProt Code: | Q969R5 |
| NCBI GenInfo Identifier: | 27734418 |
| NCBI Gene ID: | 83746 |
| NCBI Accession: | Q969R5.1 |
| UniProt Secondary Accession: | Q969R5,Q8TEN1, Q96SC4, Q9BQI2, Q9UGS4, |
| UniProt Related Accession: | Q969R5 |
| Molecular Weight: | 79kDa |
| NCBI Full Name: | Lethal(3)malignant brain tumor-like protein 2 |
| NCBI Synonym Full Names: | L3MBTL2 polycomb repressive complex 1 subunit |
| NCBI Official Symbol: | L3MBTL2 |
| NCBI Official Synonym Symbols: | L3MBT; H-l(3)mbt-l |
| NCBI Protein Information: | lethal(3)malignant brain tumor-like protein 2 |
| UniProt Protein Name: | Lethal(3)malignant brain tumor-like protein 2 |
| Protein Family: | Lethal(3)malignant brain tumor-like protein |
| UniProt Gene Name: | L3MBTL2 |
| Antibodies |
| Anti-L3MBTL2 Antibody (CAB10331) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
