Description
| 抗体名: | KLF8 Antibody |
| 抗体コード: | PACO03390 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | IHC:1:100-1:300 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human KLF8. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | KLF8; BKLF3; ZNF741; Krueppel-like factor 8; Basic krueppel-like factor 3; Zinc finger protein 741 |
| UniProt Protein Function: | KLF8: Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). Belongs to the Sp1 C2H2-type zinc-finger protein family. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: Xp11.21 Cellular Component: nucleus Molecular Function:DNA binding; metal ion binding Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| UniProt Code: | O95600 |
| NCBI GenInfo Identifier: | 17366251 |
| NCBI Gene ID: | 11279 |
| NCBI Accession: | O95600.2 |
| UniProt Related Accession: | O95600 |
| Molecular Weight: | Calculated: 26kDa; 27kDa; 30kDa; 39kDaObserved: 45kDa |
| NCBI Full Name: | Krueppel-like factor 8 |
| NCBI Synonym Full Names: | Kruppel like factor 8 |
| NCBI Official Symbol: | KLF8 |
| NCBI Official Synonym Symbols: | BKLF3; ZNF741 |
| NCBI Protein Information: | Krueppel-like factor 8 |
| UniProt Protein Name: | Krueppel-like factor 8 |
| UniProt Synonym Protein Names: | Basic krueppel-like factor 3; Zinc finger protein 741 |
| Protein Family: | Krueppel-like factor |
| UniProt Gene Name: | KLF8 |
| UniProt Entry Name: | KLF8_HUMAN |
