Description
| 抗体名: | KLF5 Antibody, FITC conjugated (PACO47876) |
| 抗体コード: | PACO47876 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Krueppel-like factor 5 protein (69-346AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
| シノニム: | Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2), KLF5, BTEB2 CKLF IKLF |
| UniProt Protein Function: | KLF5: Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 13q22.1 Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; cytoplasm; plasma membrane Molecular Function:protein binding; metal ion binding Biological Process: transcription from RNA polymerase II promoter; microvillus biogenesis; positive regulation of cell proliferation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; regulation of microvillus biogenesis |
| NCBI Summary: | This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
| UniProt Code: | Q13887 |
| NCBI GenInfo Identifier: | 12644412 |
| NCBI Gene ID: | 688 |
| NCBI Accession: | Q13887.2 |
| UniProt Secondary Accession: | Q13887,Q9UHP8, L0R3U5, L0R4T9, |
| UniProt Related Accession: | Q13887 |
| Molecular Weight: | 457 |
| NCBI Full Name: | Krueppel-like factor 5 |
| NCBI Synonym Full Names: | Kruppel-like factor 5 (intestinal) |
| NCBI Official Symbol: | KLF5 |
| NCBI Official Synonym Symbols: | CKLF; IKLF; BTEB2 |
| NCBI Protein Information: | Krueppel-like factor 5; Klf5C isoform; BTE-binding protein 2; GC box binding protein 2; colon kruppel-like factor; colon krueppel-like factor; transcription factor BTEB2; intestinal-enriched kruppel-like factor; intestinal-enriched krueppel-like factor; b |
| UniProt Protein Name: | Krueppel-like factor 5 |
| UniProt Synonym Protein Names: | Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2 |
| Protein Family: | Krueppel-like factor |
| UniProt Gene Name: | KLF5 |
| UniProt Entry Name: | KLF5_HUMAN |
