Description
| 抗体名: | KIF20A Antibody (PACO53302) |
| 抗体コード: | PACO53302 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IP |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:50-1:200, IP:1:200-1:2000 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Kinesin-like protein KIF20A protein (161-294AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO53302 at dilution of 1:100. |
 | Immunoprecipitating KIF20A in 293 whole cell lysate. Lane 1: Rabbit control IgG (1µg) instead of PACO53302 in 293 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000). Lane 2: PACO53302 (6µg) + 293 whole cell lysate (500µg). Lane 3: 293 whole cell lysate (10µg). |
| バックグラウンド: | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| シノニム: | Kinesin-like protein KIF20A (GG10_2) (Mitotic kinesin-like protein 2) (MKlp2) (Rab6-interacting kinesin-like protein) (Rabkinesin-6), KIF20A, MKLP2 RAB6KIFL |
| UniProt Protein Function: | KIF20A: Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. Belongs to the kinesin-like protein family. |
| UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 5q31 Cellular Component: kinesin complex; midbody; nucleoplasm; spindle Molecular Function:ATPase activity; microtubule motor activity; protein binding; protein kinase binding; transporter activity Biological Process: cell separation during cytokinesis; cytokinesis; cytokinesis after mitosis; microtubule bundle formation; microtubule-based movement; vesicle-mediated transport |
| UniProt Code: | O95235 |
| NCBI GenInfo Identifier: | 6225915 |
| NCBI Gene ID: | 10112 |
| NCBI Accession: | O95235.1 |
| UniProt Secondary Accession: | O95235,B4DL79, D3DQB6, |
| UniProt Related Accession: | O95235 |
| Molecular Weight: | 98,100 Da |
| NCBI Full Name: | Kinesin-like protein KIF20A |
| NCBI Synonym Full Names: | kinesin family member 20A |
| NCBI Official Symbol: | KIF20A |
| NCBI Official Synonym Symbols: | MKLP2; RAB6KIFL |
| NCBI Protein Information: | kinesin-like protein KIF20A |
| UniProt Protein Name: | Kinesin-like protein KIF20A |
| UniProt Synonym Protein Names: | GG10_2; Mitotic kinesin-like protein 2; MKlp2; Rab6-interacting kinesin-like protein; Rabkinesin-6 |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF20A |
| UniProt Entry Name: | KI20A_HUMAN |
| Antibodies | ELISA Kits |
| Anti-KIF20A Antibody (CAB15377) | KIF20A Colorimetric Cell-Based ELISA Kit |
| Phospho-KIF20A (S528) Antibody (PACO02295) | |
| KIF20A Antibody (PACO02296) | |
| KIF20A Antibody (PACO10098) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
