The KIF13B Monoclonal Antibody (PAC057496) is a valuable tool for researchers studying KIF13B, a kinesin motor protein involved in intracellular transport processes. This antibody, produced through monoclonal antibody technology, exhibits high specificity and sensitivity towards human samples, making it ideal for use in various experimental techniques such as Western blotting and immunofluorescence.KIF13B is known to play a critical role in the transport of vesicles and organelles within cells, contributing to cellular processes such as cell division, signaling, and protein trafficking.
Dysregulation of KIF13B has been implicated in various diseases including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.By utilizing the KIF13B Monoclonal Antibody, researchers can effectively detect and analyze KIF13B expression and localization in different cell types and tissues. This antibody is a valuable tool for advancing our understanding of the role of KIF13B in cellular physiology and disease pathology, ultimately paving the way for the development of novel treatment strategies.
IHC image of PACO57496 diluted at 1:400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system.
Immunofluorescence staining of A549 cells with PACO57496 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
Synonyms:
Kinesin-like protein KIF13B (Kinesin-like protein GAKIN), KIF13B, GAKIN KIAA0639
UniProt Protein Function:
Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
