Description
| 抗体名: | IVL Antibody (PACO54842) |
| 抗体コード: | PACO54842 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Involucrin protein (24-118AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: NIH/3T3 whole cell lysate. All lanes: IVL antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69 kDa. Observed band size: 69 kDa. |
 | Immunofluorescent analysis of Hela cells using PACO54842 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO54842 at dilution of 1:100. |
| バックグラウンド: | Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. |
| シノニム: | Involucrin, IVL |
| UniProt Protein Function: | IVL: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Belongs to the involucrin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; cornified envelope Molecular Function:protein binding, bridging; structural molecule activity Biological Process: keratinocyte differentiation; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; keratinization; peptide cross-linking; response to UV-B |
| NCBI Summary: | Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P07476 |
| NCBI GenInfo Identifier: | 254763301 |
| NCBI Gene ID: | 3713 |
| NCBI Accession: | P07476.2 |
| UniProt Secondary Accession: | P07476,Q5T7P4, |
| UniProt Related Accession: | P07476 |
| Molecular Weight: | 68,479 Da |
| NCBI Full Name: | Involucrin |
| NCBI Synonym Full Names: | involucrin |
| NCBI Official Symbol: | IVL |
| NCBI Protein Information: | involucrin |
| UniProt Protein Name: | Involucrin |
| Protein Family: | Involucrin |
| UniProt Gene Name: | IVL |
| UniProt Entry Name: | INVO_HUMAN |
| Antibodies | ELISA Kits |
| Anti-IVL Antibody (CAB8026) | Human INV / Involucrin ELISA Kit |
| IVL Antibody (PACO00975) | Human Involucrin (IVL) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
