Description
| 抗体名: | ITGAX Antibody (PACO10005) |
| 抗体コード: | PACO10005 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human ITGAX |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | integrin, α X (complement component 3 receptor 4 subunit);ITGAX;CD11C;SLEB6 ; |
| UniProt Protein Function: | ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cell surface; membrane; plasma membrane Molecular Function:protein binding; receptor activity Biological Process: cell adhesion; extracellular matrix organization and biogenesis; heterotypic cell-cell adhesion; leukocyte migration; organ morphogenesis Disease: Systemic Lupus Erythematosus |
| NCBI Summary: | This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
| UniProt Code: | P20702 |
| NCBI GenInfo Identifier: | 146345441 |
| NCBI Gene ID: | 3687 |
| NCBI Accession: | P20702.3 |
| UniProt Secondary Accession: | P20702,Q8IVA6, |
| UniProt Related Accession: | P20702 |
| Molecular Weight: | 127,829 Da |
| NCBI Full Name: | Integrin alpha-X |
| NCBI Synonym Full Names: | integrin subunit alpha X |
| NCBI Official Symbol: | ITGAX |
| NCBI Official Synonym Symbols: | CD11C; SLEB6 |
| NCBI Protein Information: | integrin alpha-X |
| UniProt Protein Name: | Integrin alpha-X |
| UniProt Synonym Protein Names: | CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c |
| UniProt Gene Name: | ITGAX |
