Description
| 抗体名: | INSRR Antibody (PACO09969) |
| 抗体コード: | PACO09969 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human INSRR |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | insulin receptor-related receptor;INSRR;IRR ; |
| UniProt Protein Function: | IRR: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. |
| UniProt Protein Details: | Protein type:Protein kinase, TK; Membrane protein, integral; Kinase, protein; Protein kinase, tyrosine (receptor); EC 2.7.10.1; TK group; InsR family Chromosomal Location of Human Ortholog: 1q21-q23 Cellular Component: integral to plasma membrane; receptor complex Molecular Function:insulin receptor substrate binding; phosphoinositide 3-kinase binding; transmembrane receptor protein tyrosine kinase activity; ATP binding Biological Process: peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; male sex determination; actin cytoskeleton reorganization; transmembrane receptor protein tyrosine kinase signaling pathway |
| UniProt Code: | P14616 |
| NCBI GenInfo Identifier: | 31657140 |
| NCBI Gene ID: | 3645 |
| NCBI Accession: | NP_055030.1 |
| UniProt Secondary Accession: | P14616,O60724, Q5VZS3, |
| UniProt Related Accession: | P14616 |
| Molecular Weight: | 143,720 Da |
| NCBI Full Name: | insulin receptor-related protein |
| NCBI Synonym Full Names: | insulin receptor-related receptor |
| NCBI Official Symbol: | INSRR |
| NCBI Official Synonym Symbols: | IRR |
| NCBI Protein Information: | insulin receptor-related protein; IR-related receptor |
| UniProt Protein Name: | Insulin receptor-related protein |
| UniProt Synonym Protein Names: | IR-related receptor |
| Protein Family: | Insulin receptor-related protein |
| UniProt Gene Name: | INSRR |
| UniProt Entry Name: | INSRR_HUMAN |
