Description
| 抗体名: | INPP4B Antibody, Biotin conjugated (PACO45937) |
| 抗体コード: | PACO45937 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Type II inositol 3,4-bisphosphate 4-phosphatase protein (1-53AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. |
| シノニム: | Type II inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II), INPP4B |
| UniProt Protein Function: | INPP4B: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. Widely expressed with highest levels occurring in the skeletal muscle and heart. Strongly inhibited by inositol hexakisphosphate. Belongs to the inositol 3,4-bisphosphate 4-phosphatase family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.66; Phosphatase, lipid Chromosomal Location of Human Ortholog: 4q31.21 Cellular Component: cytoplasm; cytosol Molecular Function:inositol-1,3,4-trisphosphate 4-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; protein binding Biological Process: inositol phosphate metabolic process; phosphatidylinositol biosynthetic process; signal transduction |
| NCBI Summary: | INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15327 |
| NCBI GenInfo Identifier: | 218512158 |
| NCBI Gene ID: | 8821 |
| NCBI Accession: | O15327.4 |
| UniProt Secondary Accession: | O15327,Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4, |
| UniProt Related Accession: | O15327 |
| Molecular Weight: | 14,740 Da |
| NCBI Full Name: | Type II inositol 3,4-bisphosphate 4-phosphatase |
| NCBI Synonym Full Names: | inositol polyphosphate-4-phosphatase type II B |
| NCBI Official Symbol: | INPP4B |
| NCBI Protein Information: | type II inositol 3,4-bisphosphate 4-phosphatase |
| UniProt Protein Name: | Type II inositol 3,4-bisphosphate 4-phosphatase |
| UniProt Synonym Protein Names: | Inositol polyphosphate 4-phosphatase type II |
| Protein Family: | Type II inositol 3,4-bisphosphate 4-phosphatase |
| UniProt Gene Name: | INPP4B |
| UniProt Entry Name: | INP4B_HUMAN |
