Description
| 抗体名: | ILF3 Antibody (PACO43281) |
| 抗体コード: | PACO43281 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Interleukin enhancer-binding factor 3 protein (785-894AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: Interleukin enhancer-binding factor 3 antibody at 3µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 96, 77, 83, 76, 75 kDa. Observed band size: 96 kDa. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43281 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO43281 at dilution of 1:100. |
| バックグラウンド: | May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid, beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. The phosphorylated form at Thr-188 and Thr-315, in concert with EIF2AK2/PKR can inhibit vesicular stomatitis virus (VSV) replication (By similarity). |
| シノニム: | Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80), ILF3, DRBF MPHOSPH4 NF90 |
| UniProt Protein Function: | NFAT90: a double-stranded RNA (dsRNA)-binding protein implicated in the regulation of gene expression. Phosphorylated in a double-stranded RNA-dependent manner possibly by PKR. Five different splice-variant isoforms have been described. |
| UniProt Protein Details: | Protein type:RNA-binding; Transcription factor; DNA-binding; Nucleolus Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; nucleolus; ribonucleoprotein complex; nucleus Molecular Function:protein binding; DNA binding; RNA binding; double-stranded RNA binding Biological Process: transcription, DNA-dependent; negative regulation of viral genome replication; positive regulation of transcription, DNA-dependent; negative regulation of translation; negative regulation of transcription, DNA-dependent; defense response to virus; protein amino acid phosphorylation |
| UniProt Code: | Q12906 |
| NCBI GenInfo Identifier: | 62512150 |
| NCBI Gene ID: | |
| NCBI Accession: | Q12906.3 |
| Molecular Weight: | |
| NCBI Full Name: | Interleukin enhancer-binding factor 3 |
| UniProt Protein Name: | Interleukin enhancer-binding factor 3 |
| UniProt Synonym Protein Names: | Double-stranded RNA-binding protein 76; DRBP76; M-phase phosphoprotein 4; MPP4; Nuclear factor associated with dsRNA; NFAR; Nuclear factor of activated T-cells 90 kDa; NF-AT-90; Translational control protein 80; TCP80 |
| Protein Family: | Interleukin enhancer-binding factor |
| UniProt Gene Name: | ILF3 |
| UniProt Entry Name: | ILF3_HUMAN |
| Antibodies | ELISA Kits |
| Anti-ILF3 Antibody (CAB14006) | Human ILF3 ELISA Kit (HUFI01861) |
| Anti-ILF3 Antibody (CAB2496) | Human ILF3 ELISA Kit |
| Anti-ILF3 Antibody (CAB8186) | |
| ILF3 Antibody (PACO01755) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
