Description
| 抗体名: | ICAM3 Antibody |
| 抗体コード: | PACO01956 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human CD50. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | ICAM3; Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD50 |
| UniProt Protein Function: | ICAM3: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. Belongs to the immunoglobulin superfamily. ICAM family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:integrin binding; protein binding; receptor binding Biological Process: cell adhesion; extracellular matrix organization and biogenesis; regulation of immune response; stimulatory C-type lectin receptor signaling pathway |
| NCBI Summary: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
| UniProt Code: | P32942 |
| NCBI GenInfo Identifier: | 206729872 |
| NCBI Gene ID: | 3385 |
| NCBI Accession: | P32942.2 |
| UniProt Secondary Accession: | P32942,Q6PD68, |
| UniProt Related Accession: | P32942 |
| Molecular Weight: | 59,541 Da |
| NCBI Full Name: | Intercellular adhesion molecule 3 |
| NCBI Synonym Full Names: | intercellular adhesion molecule 3 |
| NCBI Official Symbol: | ICAM3 |
| NCBI Official Synonym Symbols: | CD50; CDW50; ICAM-R |
| NCBI Protein Information: | intercellular adhesion molecule 3 |
| UniProt Protein Name: | Intercellular adhesion molecule 3 |
| UniProt Synonym Protein Names: | CDw50; ICAM-R; CD_antigen: CD50 |
| UniProt Gene Name: | ICAM3 |
