Description
| Product Name: | Human ZG16 Recombinant Protein |
| Product Code: | RPPB5183 |
| Size: | 10µg |
| Species: | Human |
| Target: | ZG16 |
| Synonyms: | Zymogen granule membrane protein 16, Zymogen granule protein 16, hZG16, Secretory lectin ZG16, ZG16, JCLN, JCLN1, ZG16A, FLJ43571, FLJ92276, MGC34820, MGC183567. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The ZG16 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSNAIQARS SSYSGEYGGG GGKRFSHSGN QLDGPITALR VRVNTYYIVG LQVRYGKVWS DYVGGRNGDL EEIFLHPGES VIQVSGKYKW YLKKLVFVTD KGRYLSFGKD SGTSFNAVPL HPNTVLRFIS GRSGSLIDAI GLHWDVYPTS CSRC |
Zymogen Granule Protein 16 Homolog (ZG16) is a member of the jacalin lectin family. ZG16 may have a role in protein trafficking and may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. ZG16 is highly expressed in the liver, but can also be detected at lower levels in colon, ileum and jejunum.
ZG16 Human Recombinant produced in E. coli is a single polypeptide chain containing 174 amino acids (17-167) and having a molecular mass of 19kDa. ZG16 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ZG16: May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. Belongs to the jacalin lectin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: extracellular matrix; Golgi lumen; proteinaceous extracellular matrix; zymogen granule membrane Molecular Function:carbohydrate binding; protein binding Biological Process: protein transport |
| UniProt Code: | O60844 |
| NCBI GenInfo Identifier: | 327412340 |
| NCBI Gene ID: | 653808 |
| NCBI Accession: | NP_689551.2 |
| UniProt Secondary Accession: | O60844,B2R4Z3, B9EK72, |
| UniProt Related Accession: | O60844 |
| Molecular Weight: | 18,147 Da |
| NCBI Full Name: | zymogen granule membrane protein 16 |
| NCBI Synonym Full Names: | zymogen granule protein 16 |
| NCBI Official Symbol: | ZG16�� |
| NCBI Official Synonym Symbols: | JCLN; JCLN1; ZG16A�� |
| NCBI Protein Information: | zymogen granule membrane protein 16 |
| UniProt Protein Name: | Zymogen granule membrane protein 16 |
| UniProt Synonym Protein Names: | Secretory lectin ZG16 |
| Protein Family: | Zymogen granule membrane protein |
| UniProt Gene Name: | ZG16�� |
| UniProt Entry Name: | ZG16_HUMAN |
