Description
| Product Name: | Human ZADH2 Recombinant Protein |
| Product Code: | RPPB5174 |
| Size: | 10µg |
| Species: | Human |
| Target: | ZADH2 |
| Synonyms: | Zinc Binding Alcohol Dehydrogenase Domain Containing 2, ZADH2, Zinc-binding alcohol dehydrogenase domain-containing protein 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The ZADH2 solution (0.25mg/1ml) contains Phosphate buffer saline (pH 7.4) and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMQKLVVT RLSPNFREAV TLSRDCPVPL PGDGDLLVRN RFVGVNASDI NYSAGRYDPS VKPPFDIGFE GIGEVVALGL SASARYTVGQ AVAYMAPGSF AEYTVVPASI ATPVPSVKPE YLTLLVSGTT AYISLKELGG LSEGKKVLVT AAAGGTGQFA MQLSKKAKCH VIGTCSSDEK SAFLKSLGCD RPINYKTEPV GTVLKQEYPE GVDVVYESVG GAMFDLAVDA LATKGRLIVI GFISGYQTPT GLSPVKAGTL PAKLLKKSAS VQGFFLNHYL SKYQAAMSHL LEMCVSGDLV CEVDLGDLSP EGRFTGLESI FRAVNYMYMG KNTGKIVVEL PHSVNSKL |
ZincBinding Alcohol Dehydrogenase Domain Containing 2, also known as ZADH2, is aprotein coding gene which is a part of the zinc-containing alcoholdehydrogenase family.
ZADH2 Human Recombinant produced in E. coli is a single polypeptide chain containing 368 amino acids (33-377) and having a molecular mass of 39kDa.ZADH2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N4Q0 |
| NCBI GenInfo Identifier: | 28557745 |
| NCBI Gene ID: | 284273 |
| NCBI Accession: | NP_787103 |
| UniProt Secondary Accession: | Q8N4Q0,A8KA15, B4DZ91 |
| UniProt Related Accession: | Q8N4Q0 |
| Molecular Weight: | 39.0kDa (368aa) confirmed by MALDI-TOF |
| NCBI Full Name: | prostaglandin reductase 3 isoform 1 |
| NCBI Synonym Full Names: | zinc binding alcohol dehydrogenase domain containing 2 |
| NCBI Official Symbol: | ZADH2�� |
| NCBI Official Synonym Symbols: | PRG-3�� |
| NCBI Protein Information: | prostaglandin reductase 3 |
| UniProt Protein Name: | Prostaglandin reductase 3 |
| UniProt Synonym Protein Names: | Zinc-binding alcohol dehydrogenase domain-containing protein 2 |
| Protein Family: | Zinc-binding alcohol dehydrogenase domain-containing protein |
| UniProt Gene Name: | ZADH2�� |
| UniProt Entry Name: |
