Description
system_update_altDatasheet
| Product name | Human XCR1 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP101 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | XCR1 |
| Uniprot: | P46094 |
| Description: | Human XCR1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length XCR1 protein has a MW of 38.3 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CCXCR1; GPR5 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
