Description
| Product Name: | Human UBE2Q2 Recombinant Protein |
| Product Code: | RPPB2388 |
| Size: | 10µg |
| Species: | Human |
| Target: | UBE2Q2 |
| Synonyms: | Ubiquitin-conjugating enzyme E2 Q2, UBE2Q2, E2 ubiquitin-conjugating enzyme Q2, Ubiquitin carrier protein Q2, Ubiquitin-protein ligase Q2, Ubiquitin Conjugating Enzyme E2Q2, Ubiquitin-conjugating enzyme E2 Q2 isoform1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | UBE2Q2 protein solution (0.5mg/ml) containing Phosphate Buffer Saline (pH7.4), 30% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSVSGLK AELKFLASIF DKNHERFRIV SWKLDELHCQ FLVPQQGSPH SLPPPLTLHC NITESYPSSS PIWFVDSEDP NLTSVLERLE DTKNNNLLRQ QLKWLICELC SLYNLPKHLD VEMLDQPLPT GQNGTTEEVT SEEEEEEEEM AEDIEDLDHY EMKEEEPISG KKSEDEGIEK ENLAILEKIR KTQRQDHLNG AVSGSVQASD RLMKELRDIY RSQSYKTGIY SVELINDSLY DWHVKLQKVD PDSPLHSDLQ ILKEKEGIEY ILLNFSFKDN FPFDPPFVRV VLPVLSGGYV LGGGALCMEL LTKQGWSSAY SIESVIMQIN ATLVKGKARV QFGANKNQYN LARAQQSYNS IVQIHEKNGW YTPPKEDG |
UbiquitinConjugating Enzyme E2Q2 (UBE2Q2) is a protein coding gene which receives ubiquitinfrom the E1 complex and catalyzes its covalent attachment to various proteins. UBE2Q2which is a part of the ubiquitin-conjugating enzyme family is detected inhypopharyngeal head and neck squamous cell carcinoma and in tumor masses.
UBE2Q2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 398 amino acids (1-375a.a.) and having a molecular mass of 45.2kDa.UBE2Q2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | UBE2Q2: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 6.3.2.19; Ubiquitin conjugating system; Ligase; Ubiquitin ligase Chromosomal Location of Human Ortholog: 15q24.2 Molecular Function:ubiquitin-protein ligase activity |
| UniProt Code: | Q8WVN8 |
| NCBI GenInfo Identifier: | 74751557 |
| NCBI Gene ID: | 92912 |
| NCBI Accession: | Q8WVN8.1 |
| UniProt Secondary Accession: | Q8WVN8,Q8N4G6, Q96J08, B7Z3Q2, H3BRG2, |
| UniProt Related Accession: | Q8WVN8 |
| Molecular Weight: | 38,699 Da |
| NCBI Full Name: | Ubiquitin-conjugating enzyme E2 Q2 |
| NCBI Synonym Full Names: | ubiquitin conjugating enzyme E2 Q2 |
| NCBI Official Symbol: | UBE2Q2�� |
| NCBI Protein Information: | ubiquitin-conjugating enzyme E2 Q2 |
| UniProt Protein Name: | Ubiquitin-conjugating enzyme E2 Q2 |
| UniProt Synonym Protein Names: | E2 ubiquitin-conjugating enzyme Q2; Ubiquitin carrier protein Q2; Ubiquitin-protein ligase Q2 |
| Protein Family: | Ubiquitin-conjugating enzyme |
| UniProt Gene Name: | UBE2Q2�� |
| UniProt Entry Name: | UB2Q2_HUMAN |
