Description
| Product Name: | Human TSSK2 Recombinant Protein |
| Product Code: | RPPB2672 |
| Size: | 10µg |
| Species: | Human |
| Target: | TSSK2 |
| Synonyms: | Testis-specific serine/threonine-protein kinase 2, DGS-G,SPOGA2, STK22B, TSK2, TSK-2, TSSK-2, TSSK2, DiGeorge syndrome protein G, Serine/threonine-proteinkinase 22B, DGSG, Testis Specific Serine Kinase 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | TSSK2 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMDDATVL RKKGYIVGIN LGKGSYAKVK SAYSERLKFN VAVKIIDRKKTPTDFVERFL PREMDILATV NHGSIIKTYE IFETSDGRIY IIMELGVQGD LLEFIKCQGA LHEDVARKMFRQLSSAVKYC HDLDIVHRDL KCENLLLDKD FNIKLSDFGF SKRCLRDSNG RIILSKTFCG SAAYAAPEVLQSIPYQPKVY DIWSLGVILY IMVCGSMPYD DSDIRKMLRI QKEHRVDFPR SKNLTCECKD LIYRMLQPDVSQRLHIDEIL SHSWLQPPKP KATSSASFKR EGEGKYRAEC KLDTKTGLRP DHRPDHKLGA KTQHRLLVVPENENRMEDRL AETSRAKDHH ISGAEVGKAS T |
| UniProt Code: | Q96PF2 |
TSSK2 is a testis-specific serine/threonine-protein kinase required during spermatid development which phosphorylates TSKS at 'Ser-288' and SPAG16. TSSK2 takes part in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, TSSK2 is necessary for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
TSSK2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 381 amino acids (1-358 a.a) and having a molecular mass of 43kDa.TSSK2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
