Description
| Product Name: | Nanodisc Human TRPV6 Protein |
| SKU: | HDFP506 |
| Size: | 10μg |
| Target: | TRPV6 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | ABP/ZF; CAT1; CATL; ECAC2; HRPTTN; HSA277909; LP6728; ZFAB |
| Protein Families: | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane. |
| Protein Description: | Human TRPV6 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length TRPV6 protein has a MW of 87.3 kDa |
A member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
| Uniprot ID: | Q9H1D0 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
