Description
| Product Name: | Human TPST2 Recombinant Protein |
| Product Code: | RPPB2346 |
| Size: | 10µg |
| Species: | Human |
| Target: | TPST2 |
| Synonyms: | Protein-tyrosine sulfotransferase 2, EC 2.8.2.20, Tyrosylprotein sulfotransferase 2, TPST-2, TPST2, TANGO13B. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The TPST2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSQQVLECR AVLAGLRSPR GAMRPEQEEL VMVGTNHVEY RYGKAMPLIF VGGVPRSGTT LMRAMLDAHP EVRCGEETRI IPRVLAMRQA WSKSGREKLR LDEAGVTDEV LDAAMQAFIL EVIAKHGEPA RVLCNKDPFT LKSSVYLSRL FPNSKFLLMV RDGRASVHSM ITRKVTIAGF DLSSYRDCLT KWNKAIEVMY AQCMEVGKEK CLPVYYEQLV LHPRRSLKLI LDFLGIAWSD AVLHHEDLIG KPGGVSLSKI ERSTDQVIKP VNLEALSKWT GHIPGDVVRD MAQIAPMLAQ LGYDPYANPP NYGNPDPFVI NNTQRVLKGD YKTPANLKGY FQVNQNSTSS HLGSS |
Tyrosylprotein Sulfotransferase 2 (TPST2) is a member of the protein sulfotransferase family. TPST2 is a widely expressed protein, which catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The TPST2 protein is a type II integral membrane protein located in the Golgi body.
TPST2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 375 amino acids (26-377) and having a molecular mass of 41kDa.TPST2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TPST2: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. Belongs to the protein sulfotransferase family. |
| UniProt Protein Details: | Protein type:EC 2.8.2.20; Endoplasmic reticulum; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 22q12.1 Cellular Component: Golgi membrane; membrane; endoplasmic reticulum; integral to membrane Molecular Function:protein-tyrosine sulfotransferase activity Biological Process: fusion of sperm to egg plasma membrane; peptidyl-tyrosine sulfation |
| NCBI Summary: | The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60704 |
| NCBI GenInfo Identifier: | 6686027 |
| NCBI Gene ID: | 8459 |
| NCBI Accession: | O60704.1 |
| UniProt Secondary Accession: | O60704,Q6FI98, Q9H0V4, B3KQA7, |
| UniProt Related Accession: | O60704 |
| Molecular Weight: | 377 |
| NCBI Full Name: | Protein-tyrosine sulfotransferase 2 |
| NCBI Synonym Full Names: | tyrosylprotein sulfotransferase 2 |
| NCBI Official Symbol: | TPST2�� |
| NCBI Official Synonym Symbols: | TANGO13B�� |
| NCBI Protein Information: | protein-tyrosine sulfotransferase 2; TPST-2; tyrosylprotein sulfotransferase-2; tyrosylprotein phosphotransferase 2; transport and golgi organization 13 homolog B |
| UniProt Protein Name: | Protein-tyrosine sulfotransferase 2 |
| UniProt Synonym Protein Names: | Tyrosylprotein sulfotransferase 2; TPST-2 |
| Protein Family: | Protein-tyrosine sulfotransferase |
| UniProt Gene Name: | TPST2�� |
| UniProt Entry Name: | TPST2_HUMAN |
