Description
| Product Name: | Human SYT3 Recombinant Protein |
| Product Code: | RPPB4888 |
| Size: | 20µg |
| Species: | Human |
| Target: | SYT3 |
| Synonyms: | Synaptotagmin III, SYT3, SytIII, synaptotagmin-3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The SYT3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSEFWKLCW VPWRDKGGSA VGGGPLRKDL GPGVGLAGLV GGGGHHLAAG LGGHPLLGGP HHHAHAAHHP PFAELLEPGS LGGSDTPEPS YLDMDSYPEA AAAAVAAGVK PSQTSPELPS EGGAGSGLLL LPPSGGGLPS AQSHQQVTSL APTTRYPALP RPLTQQTLTS QPDPSSEERP PALPLPLPGG EEKAKLIGQI KPELYQGTGP GGRRSGGGPG SGEAGTGAPC GRISFALRYL YGSDQLVVRI LQALDLPAKD SNGFSDPYVK IYLLPDRKKK FQTKVHRKTL NPVFNETFQF SVPLAELAQR KLHFSVYDFD RFSRHDLIGQ VVLDNLLELA EQPPDRPLWR DIVEGGSEKA DLGELNFSLC YLPTAGRLTV TIIKASNLKA MDLTGFSDPY VKASLISEGR RLKKRKTSIK KNTLNPTYNE ALVFDVAPES VENVGLSIAV VDYDCIGHNE VIGVCRVGPD AADPHGREHW AEMLANPRKP VEHWHQLVEE KTVTSFTKGS KGLSEKENSE |
Synaptotagmin-3 (SYT3) is a member of the synaptotagmin family. SYT3 is involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may function as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
SYT3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 540 amino acids (76-590) and having a molecular mass of 57.7 kDa.SYT3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SYT3: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Vesicle; Calcium-binding Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: synaptic vesicle membrane; integral to membrane; cell junction; endosome Molecular Function:clathrin binding; syntaxin binding; calcium-dependent phospholipid binding; phosphatidylserine binding; transporter activity; metal ion binding Biological Process: positive regulation of vesicle fusion; response to calcium ion; calcium ion-dependent exocytosis |
| UniProt Code: | Q9BQG1 |
| NCBI GenInfo Identifier: | 18202733 |
| NCBI Gene ID: | 84258 |
| NCBI Accession: | Q9BQG1.1 |
| UniProt Secondary Accession: | Q9BQG1,Q8N5Z1, Q8N640, |
| UniProt Related Accession: | Q9BQG1 |
| Molecular Weight: | 63,304 Da |
| NCBI Full Name: | Synaptotagmin-3 |
| NCBI Synonym Full Names: | synaptotagmin III |
| NCBI Official Symbol: | SYT3�� |
| NCBI Official Synonym Symbols: | SytIII�� |
| NCBI Protein Information: | synaptotagmin-3 |
| UniProt Protein Name: | Synaptotagmin-3 |
| UniProt Synonym Protein Names: | Synaptotagmin III; SytIII |
| Protein Family: | Synaptotagmin |
| UniProt Gene Name: | SYT3�� |
| UniProt Entry Name: | SYT3_HUMAN |
