Description
| Product Name: | Human SYNJ2BP Recombinant Protein |
| Product Code: | RPPB4886 |
| Size: | 20µg |
| Species: | Human |
| Target: | SYNJ2BP |
| Synonyms: | Synaptojanin 2 binding protein, ARIP2, OMP25, Synaptojanin-2-binding protein, Mitochondrial outer membrane protein 25, SYNJ2BP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | SYNJ2BP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNGRVDY LVTEEEINLT RGPSGLGFNI VGGTDQQYVS NDSGIYVSRI KENGAAALDG RLQEGDKILS VNGQDLKNLL HQDAVDLFRN AGYAVSLRVQ HRLQVQNGPI GHRGEGDPSG |
Synaptojanin 2 Binding Protein (SYNJ2BP) contains 1 PDZ (DHR) domain which binds to isoform 2A of SYNJ2 (through the unique motif in the C-terminus) and interacts with MAPK12.
SYNJ2BP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids (1-117 a.a) and having a molecular mass of 15.0kDa. SYNJ2BP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SYNJ2BP: Binds (via the PDZ domain) to isoform 2A of SYNJ2 (via the unique motif in the C-terminus). |
| UniProt Protein Details: | Protein type:Adaptor/scaffold; Mitochondrial; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q24.2 Cellular Component: mitochondrion Molecular Function:protein binding Biological Process: negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; regulation of Notch signaling pathway |
| UniProt Code: | P57105 |
| NCBI GenInfo Identifier: | 22261816 |
| NCBI Gene ID: | 55333 |
| NCBI Accession: | P57105.2 |
| UniProt Secondary Accession: | P57105,Q49SH3, Q96IA4, |
| UniProt Related Accession: | P57105 |
| Molecular Weight: | 15928 Da |
| NCBI Full Name: | Synaptojanin-2-binding protein |
| NCBI Synonym Full Names: | synaptojanin 2 binding protein |
| NCBI Official Symbol: | SYNJ2BP�� |
| NCBI Official Synonym Symbols: | ARIP2; OMP25�� |
| NCBI Protein Information: | synaptojanin-2-binding protein |
| UniProt Protein Name: | Synaptojanin-2-binding protein |
| UniProt Synonym Protein Names: | Mitochondrial outer membrane protein 25 |
| Protein Family: | Synaptojanin-2-binding protein |
| UniProt Gene Name: | SYNJ2BP�� |
| UniProt Entry Name: | SYJ2B_HUMAN |
