Description
| Product Name: | Human SYF2 Recombinant Protein |
| Product Code: | RPPB4885 |
| Size: | 5µg |
| Species: | Human |
| Target: | SYF2 |
| Synonyms: | Pre-mRNA-splicing factor SYF2, CCNDBP1-interactor, p29, SYF2, CBPIN, GCIPIP, NTC31, fSAP29. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SYF2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.2M NaCl, 5mM DTT and 2mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSDYEKVKL LEISAEDAER WERKKKRKNP DLGFSDYAAA QLRQYHRLTK QIKPDMETYE RLREKHGEEF FPTSNSLLHG THVPSTEEID RMVIDLEKQI EKRDKYSRRR PYNDDADIDY INERNAKFNK KAERFYGKYT AEIKQNLERG TAV |
Pre-mRNA-splicing factor SYF2 (SYF2) may be involved in pre-mRNA splicing. The SYF2 protein interacts with cyclin D-type binding-protein 1, which is believed to be a cell cycle regulator at the G1/S transition. SYF2 is amply expressed in the heart, skeletal muscle and kidney and is expressed at lower levels in other tissues.
SYF2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 173 amino acids (94-243) and having a molecular mass of 20.5kDa.SYF2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SYF2: May be involved in pre-mRNA splicing. Belongs to the SYF2 family. |
| UniProt Protein Details: | Protein type:RNA-binding; RNA processing; RNA splicing; Spliceosome Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: nucleus Biological Process: nuclear mRNA splicing, via spliceosome; in utero embryonic development; mitotic cell cycle G2/M transition DNA damage checkpoint; embryonic organ development; gastrulation |
| NCBI Summary: | This gene encodes a nuclear protein that interacts with cyclin D-type binding-protein 1, which is thought to be a cell cycle regulator at the G1/S transition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95926 |
| NCBI GenInfo Identifier: | 7661636 |
| NCBI Gene ID: | 25949 |
| NCBI Accession: | NP_056299.1 |
| UniProt Related Accession: | O95926 |
| Molecular Weight: | 23kDa; 28kDa |
| NCBI Full Name: | pre-mRNA-splicing factor SYF2 isoform 1 |
| NCBI Synonym Full Names: | SYF2 pre-mRNA splicing factor |
| NCBI Official Symbol: | SYF2�� |
| NCBI Official Synonym Symbols: | P29; CBPIN; NTC31; fSAP29�� |
| NCBI Protein Information: | pre-mRNA-splicing factor SYF2 |
| UniProt Protein Name: | Pre-mRNA-splicing factor SYF2 |
| UniProt Synonym Protein Names: | CCNDBP1-interactor; p29 |
| Protein Family: | Pre-mRNA-splicing factor |
| UniProt Gene Name: | SYF2�� |
| UniProt Entry Name: | SYF2_HUMAN |
