Description
| Product Name: | Human STX6 Recombinant Protein |
| Product Code: | RPPB4869 |
| Size: | 20µg |
| Species: | Human |
| Target: | STX6 |
| Synonyms: | Syntaxin 6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The STX6 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 2mM DTT and 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSMEDPF FVVKGEVQKA VNTAQGLFQR WTELLQDPST ATREEIDWTT NELRNNLRSI EWDLEDLDET ISIVEANPRK FNLDATELSI RKAFITSTRQ VVRDMKDQMS TSSVQALAER KNRQALLGDS GSQNWSTGTT DKYGRLDREL QRANSHFIEE QQAQQQLIVE QQDEQLELVS GSIGVLKNMS QRIGGELEEQ AVMLEDFSHE LESTQSRLDN VMKKLAKVSH MTSDRRQ |
STX6 is a member of the syntaxin family and has 1 t-SNARE coiled-coil homology domain. STX6 takes part in intracellular vesicle transferring. STX6 binds EEA1 and Interacts with VPS45A, MARCH2, MARCH3 and GOPC. It is found in a complex comprising STX6, STX12, VAMP4 and VTI1A.
STX6 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 257 amino acids (1-234) and having a molecular mass of 29.2kDa.STX6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | STX6: Involved in intracellular vesicle trafficking. Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3. Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Belongs to the syntaxin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 1q25.3 Cellular Component: clathrin-coated vesicle; early endosome; Golgi apparatus; Golgi membrane; integral to membrane; perinuclear region of cytoplasm; plasma membrane; SNARE complex; trans-Golgi network; trans-Golgi network membrane Molecular Function:protein binding; SNAP receptor activity; syntaxin binding Biological Process: endocytic recycling; intracellular protein transport; regulation of protein localization; retrograde transport, endosome to Golgi; vesicle docking; vesicle fusion |
| UniProt Code: | O43752 |
| NCBI GenInfo Identifier: | 6226190 |
| NCBI Gene ID: | 10228 |
| NCBI Accession: | O43752.1 |
| UniProt Secondary Accession: | O43752,Q5VY08, Q6FH83, B2R652, B4DR17, |
| UniProt Related Accession: | O43752 |
| Molecular Weight: | 17,434 Da |
| NCBI Full Name: | Syntaxin-6 |
| NCBI Synonym Full Names: | syntaxin 6 |
| NCBI Official Symbol: | STX6�� |
| NCBI Protein Information: | syntaxin-6 |
| UniProt Protein Name: | Syntaxin-6 |
| Protein Family: | Syntaxin |
| UniProt Gene Name: | STX6�� |
| UniProt Entry Name: | STX6_HUMAN |
