Description
| Product Name: | Human SPIN1 Recombinant Protein |
| Product Code: | RPPB4805 |
| Size: | 5µg |
| Species: | Human |
| Target: | SPIN1 |
| Synonyms: | Ovarian cancer-related protein, spindlin 1, SPIN, OCR. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SPIN1 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMKTPFGK TPGQRSRADA GHAGVSANMM KKRTSHKKHR SSVGPSKPVS QPRRNIVGCR IQHGWKEGNG PVTQWKGTVL DQVPVNPSLY LIKYDGFDCV YGLELNKDER VSALEVLPDR VATSRISDAH LADTMIGKAV EHMFETEDGS KDEWRGMVLA RAPVMNTWFY ITYEKDPVLY MYQLLDDYKE GDLRIMPDSN DSPPAEREPG EVVDSLVGKQ VEYAKEDGSK RTGMVIHQVE AKPSVYFIKF DDDFHIYVYD LVKTS |
SPIN1 is a member of the SPIN/STSY family. SPIN1 is localized to nucleus, and expressed in several tissues and cells. SPIN1 takes part in cell-cycle regulation in the course of the transition from gamete to embryo.
SPIN1 Human Recombinant produced E. coli is a single polypeptide chain containing 285 amino acids (1-262) and having a molecular mass of 32.0kDa.SPIN1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SPIN1: May play a role in cell-cycle regulation during the transition from gamete to embryo. Belongs to the SPIN/STSY family. |
| UniProt Protein Details: | Protein type:Nucleolus; DNA-binding Chromosomal Location of Human Ortholog: 9q22.1 Cellular Component: nucleolus; spindle; nucleus Molecular Function:protein binding; methylated histone residue binding Biological Process: Wnt receptor signaling pathway; meiotic cell cycle; multicellular organismal development; gamete generation; chromatin modification; positive regulation of Wnt receptor signaling pathway; rRNA transcription |
| UniProt Code: | Q9Y657 |
| NCBI GenInfo Identifier: | 93141317 |
| NCBI Gene ID: | 10927 |
| NCBI Accession: | Q9Y657.3 |
| UniProt Secondary Accession: | Q9Y657,Q7KZJ8, Q9GZT2, Q9H0N7, A8K0X6, B3KRQ4, |
| UniProt Related Accession: | Q9Y657 |
| Molecular Weight: | Calculated MW: 29kDaObserved MW: 32kDa |
| NCBI Full Name: | Spindlin-1 |
| NCBI Synonym Full Names: | spindlin 1 |
| NCBI Official Symbol: | SPIN1�� |
| NCBI Official Synonym Symbols: | SPIN�� |
| NCBI Protein Information: | spindlin-1; ovarian cancer-related protein; spindlin1 |
| UniProt Protein Name: | Spindlin-1 |
| UniProt Synonym Protein Names: | Ovarian cancer-related protein; Spindlin1 |
| Protein Family: | Spindlin |
| UniProt Gene Name: | SPIN1�� |
| UniProt Entry Name: | SPIN1_HUMAN |
