Description
| Product Name: | Human SFRP5 Recombinant Protein |
| Product Code: | RPPB4657 |
| Size: | 20µg |
| Species: | Human |
| Target: | SFRP5 |
| Synonyms: | Secreted Frizzled-Related Protein 5, SARP3, Secreted Apoptosis Related Protein 3, Secreted Apoptosis-Related Protein 3, Frizzled-Related Protein 1b, FRP-1b, SARP-3, SFRP-5, FRP1B, SFRP5. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | SFRP5 protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSEEYDYYG WQAEPLHGRS YSKPPQCLDI PADLPLCHTV GYKRMRLPNL LEHESLAEVK QQASSWLPLL AKRCHSDTQV FLCSLFAPVC LDRPIYPCRS LCEAVRAGCA PLMEAYGFPW PEMLHCHKFP LDNDLCIAVQ FGHLPATAPP VTKICAQCEM EHSADGLMEQ MCSSDFVVKM RIKEIKIENG DRKLIGAQKK KKLLKPGPLK RKDTKRLVLH MKNGAGCPCP QLDSLAGSFL VMGRKVDGQL LLMAVYRWDK KNKEMKFAVK FMFSYPCSLY YPFFYGAAEP H |
Secreted Frizzled-Related Protein 5, also known as SFRP5, belongs to theSFRP family which includes a cysteine-rich domain homologous to the putativeWnt-binding site of Frizzled proteins. SFRPs perform like soluble modulatorsof� Wnt signaling. SFRP5 & SFRP1 areimplicated in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in theretinal pigment epithelium, as well as moderately expressed in the pancreas.�
SFRP5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 311 amino acids (30-317 a.a) and having a molecular mass of 35kDa.SFRP5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Code: | Q5T4F7 |
| NCBI GenInfo Identifier: | 188528609 |
| NCBI Gene ID: | 6425 |
| NCBI Accession: | NP_003006.2 |
| UniProt Secondary Accession: | Q5T4F7,O14780, Q86TH7, |
| UniProt Related Accession: | Q5T4F7 |
| Molecular Weight: | 35,563 Da |
| NCBI Full Name: | secreted frizzled-related protein 5 |
| NCBI Synonym Full Names: | secreted frizzled-related protein 5 |
| NCBI Official Symbol: | SFRP5�� |
| NCBI Official Synonym Symbols: | SARP3�� |
| NCBI Protein Information: | secreted frizzled-related protein 5; FRP-1b; SARP-3; sFRP-5; frizzled-related protein 1b; secreted apoptosis related protein 3; secreted apoptosis-related protein 3 |
| UniProt Protein Name: | Secreted frizzled-related protein 5 |
| UniProt Synonym Protein Names: | Frizzled-related protein 1b; FRP-1b; Secreted apoptosis-related protein 3 |
| Protein Family: | Secreted frizzled-related protein |
| UniProt Gene Name: | SFRP5�� |
| UniProt Entry Name: | SFRP5_HUMAN |
