Description
| Product Name: | Human SF20 Recombinant Protein |
| Product Code: | RPPB0952 |
| Size: | 50µg |
| Species: | Human |
| Target: | SF20 |
| Synonyms: | C19orf10, Interleukin-25, IL-25, IL25, IL27, IL-27, IL27w, IL-27w, Stromal cell-derived growth factor SF20, UPF0556 protein C19orf10, chromosome 19 open reading frame 10. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | C9orf10 is supplied in 20mM Tris HCL pH-8 and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Purity: | Greater than 95.0% by SDS-PAGE. |
SF20 plays a role in proliferation of lymphoid cells and is considered an interleukin. SF20 was initially identified as a product of bone marrow-derived stromal cells.
SF20 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 162 amino acids fragment (33-173) and having a total molecular mass of 18 kDa. C9orf10 is fused to 20 amino acids His tag at N-terminus and is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MYDGF: was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: extracellular space; endoplasmic reticulum lumen; ER-Golgi intermediate compartment Biological Process: positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; positive regulation of MAPKKK cascade; unfolded protein response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid phosphorylation; negative regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q969H8 |
| NCBI GenInfo Identifier: | 61221730 |
| NCBI Gene ID: | 56005 |
| NCBI Accession: | Q969H8.1 |
| UniProt Related Accession: | Q969H8 |
| Molecular Weight: | |
| NCBI Full Name: | Myeloid-derived growth factor |
| NCBI Synonym Full Names: | myeloid derived growth factor |
| NCBI Official Symbol: | MYDGF�� |
| NCBI Official Synonym Symbols: | IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335�� |
| NCBI Protein Information: | myeloid-derived growth factor |
| UniProt Protein Name: | UPF0556 protein C19orf10 |
| UniProt Synonym Protein Names: | Interleukin-25; IL-25; Stromal cell-derived growth factor SF20 |
| Protein Family: | Myeloid-derived growth factor |
| UniProt Gene Name: | C19orf10�� |
| UniProt Entry Name: | CS010_HUMAN |
