Description
| Product Name: | Human RPS4X Recombinant Protein |
| Product Code: | RPPB4509 |
| Size: | 20µg |
| Species: | Human |
| Target: | RPS4X |
| Synonyms: | Ribosomal protein S4, X-linked, CCG2; DXS306, RPS4, S4, SCAR, SCR10, 40S ribosomal protein S4, X isoform, Single copy abundant mRNA protein, RPS4X. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The RPS4X solution (0.5mg/ml) contains 20mM Tris-HCl(pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMARGPKK HLKRVAAPKH WMLDKLTGVF APRPSTGPHK LRECLPLIIF LRNRLKYALT GDEVKKICMQ RFIKIDGKVR TDITYPAGFM DVISIDKTGE NFRLIYDTKG RFAVHRITPE EAKYKLCKVR KIFVGTKGIP HLVTHDARTI RYPDPLIKVN DTIQIDLETG KITDFIKFDT GNLCMVTGGA NLGRIGVITN RERHPGSFDV VHVKDANGNS FATRLSNIFV IGKGNKPWIS LPRGKGIRLT IAEERDKRLA AKQSSG |
Ribosomal Protein 4X (RPS4X) is ribosomal protein S4, a component of the 40S subunit which is a part from the S4E family of ribosomal proteins. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, that is RPS4X and ribosomal protein S4, Y-linked (RPS4Y). Both isoforms encoded by these genes are not the same, but are functionally alike.��
RPS4X Human Recombinant produced in E. coli is a single polypeptide chain containing 286 amino acids (1-263) and having a molecular mass of 32kDa. RPS4X is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPS4X: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Translation; RNA-binding Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytosol; focal adhesion; membrane; nucleoplasm; polysome; ribonucleoprotein complex; ribosome; small ribosomal subunit Molecular Function:protein binding; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; multicellular organismal development; positive regulation of cell proliferation; positive regulation of translation; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
| NCBI Summary: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P62701 |
| NCBI GenInfo Identifier: | 50403628 |
| NCBI Gene ID: | 6191 |
| NCBI Accession: | P62701.2 |
| UniProt Secondary Accession: | P62701,P12631, P12750, P27576, P55831, Q14727, Q6IPY4 |
| UniProt Related Accession: | P62701 |
| Molecular Weight: | 29,598 Da |
| NCBI Full Name: | 40S ribosomal protein S4, X isoform |
| NCBI Synonym Full Names: | ribosomal protein S4, X-linked |
| NCBI Official Symbol: | RPS4X�� |
| NCBI Official Synonym Symbols: | S4; CCG2; RPS4; SCAR; SCR10; DXS306�� |
| NCBI Protein Information: | 40S ribosomal protein S4, X isoform |
| UniProt Protein Name: | 40S ribosomal protein S4, X isoform |
| UniProt Synonym Protein Names: | SCR10; Single copy abundant mRNA protein |
| Protein Family: | 40S ribosomal protein |
| UniProt Gene Name: | RPS4X�� |
| UniProt Entry Name: | RS4X_HUMAN |
