Description
| Product Name: | Human RPL18A Recombinant Protein |
| Product Code: | RPPB4492 |
| Size: | 20µg |
| Species: | Human |
| Target: | RPL18A |
| Synonyms: | Ribosomal Protein L18a, Ribosomal Protein L18a-Like Protein, 60S Ribosomal Protein L18a, L18A, RPL18A. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The RPL18A solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMKASGTL REYKVVGRCL PTPKCHTPPL YRMRIFAPNH VVAKSRFWYF VSQLKKMKKS SGEIVYCGQV FEKSPLRVKN FGIWLRYDSR SGTHNMYREY RDLTTAGAVT QCYRDMGARH RARAHSIQIM KVEEIAASKC RRPAVKQFHD SKIKFPLPHR VLRRQHKPRF TTKRPNTFF |
Ribosomal Protein L18A (RPL18A) is a ribosomal protein which is a component of the 60S subunit, belongs to the L18AE family of ribosomal proteins. RPL18A is located in the cytoplasm. RPL18A is co-transcribed with the U68 snoRNA, which is located in its 3rd intron. The RPL18A protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES).
RPL18A Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 199 amino acids (1-176) and having a molecular mass of 23.2 kDa.RPL18A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPL18A: a ribosomal protein of the L18AE family. Located in the cytoplasm. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 60S subunit. |
| UniProt Protein Details: | Protein type:Translation; Ribosomal Chromosomal Location of Human Ortholog: 19p13 Cellular Component: membrane; cytosol Molecular Function:structural constituent of ribosome; RNA binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; translation; viral reproduction; translational initiation; mRNA catabolic process, nonsense-mediated decay; viral transcription; gene expression; viral infectious cycle; translational termination |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18AE family of ribosomal proteins that is a component of the 60S subunit. The encoded protein may play a role in viral replication by interacting with the hepatitis C virus internal ribosome entry site (IRES). This gene is co-transcribed with the U68 snoRNA, located within the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q02543 |
| NCBI GenInfo Identifier: | 730538 |
| NCBI Gene ID: | 6142 |
| NCBI Accession: | Q02543.2 |
| UniProt Related Accession: | Q02543 |
| Molecular Weight: | |
| NCBI Full Name: | 60S ribosomal protein L18a |
| NCBI Synonym Full Names: | ribosomal protein L18a |
| NCBI Official Symbol: | RPL18A�� |
| NCBI Official Synonym Symbols: | L18A�� |
| NCBI Protein Information: | 60S ribosomal protein L18a |
| UniProt Protein Name: | 60S ribosomal protein L18a |
| UniProt Gene Name: | RPL18A�� |
| UniProt Entry Name: | RL18A_HUMAN |
