Description
| Product Name: | Human RNF114 Recombinant Protein |
| Product Code: | RPPB4481 |
| Size: | 20µg |
| Species: | Human |
| Target: | RNF114 |
| Synonyms: | E3 ubiquitin-protein ligase RNF114, RING finger protein 114, Zinc finger protein 228, Zinc finger protein 313, RNF114, ZNF228, ZNF313, PSORS12. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | RNF114 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAAQQRD CGGAAQLAGP AAEADPLGRF TCPVCLEVYE KPVQVPCGHV FCSACLQECL KPKKPVCGVC RSALAPGVRA VELERQIEST ETSCHGCRKN FFLSKIRSHV ATCSKYQNYI MEGVKATIKD ASLQPRNVPN RYTFPCPYCP EKNFDQEGLV EHCKLFHSTD TKSVVCPICA SMPWGDPNYR SANFREHIQR RHRFSYDTFV DYDVDEEDMM NQVLQRSIID Q |
Ring Finger Protein 114 (RNF114) is expressed in various tissues, including skin, CD4 lymphocytes and dendritic cells. RNF114, which contains 1 RING-type zinc finger, takes part in spermatogenesis.
RNF114 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 251 amino acids (1-228 a.a) and having a molecular mass of 28.1kDa.RNF114 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ZNF313: May play a role in spermatogenesis. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; Ubiquitin ligase; Transcription factorChromosomal Location of Human Ortholog: 20q13.13Cellular Component: cytosol; intracellularMolecular Function: ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activityBiological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y508 |
| NCBI GenInfo Identifier: | 8923898 |
| NCBI Gene ID: | 55905 |
| NCBI Accession: | NP_061153.1 |
| UniProt Secondary Accession: | Q9Y508,Q6N0B0, B2RDQ9, B4DWY5, E1P627 |
| UniProt Related Accession: | Q9Y508 |
| Molecular Weight: | 21,004 Da |
| NCBI Full Name: | E3 ubiquitin-protein ligase RNF114 |
| NCBI Synonym Full Names: | ring finger protein 114 |
| NCBI Official Symbol: | RNF114�� |
| NCBI Official Synonym Symbols: | ZNF313; PSORS12�� |
| NCBI Protein Information: | E3 ubiquitin-protein ligase RNF114 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase RNF114 |
| UniProt Synonym Protein Names: | RING finger protein 114; Zinc finger protein 228; Zinc finger protein 313 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | RNF114�� |
| UniProt Entry Name: | RN114_HUMAN |
