Description
| Product Name: | Human PRPSAP2 Recombinant Protein |
| Product Code: | RPPB4479 |
| Size: | 20µg |
| Species: | Human |
| Target: | PRPSAP2 |
| Synonyms: | PAP41, Phosphoribosyl pyrophosphate synthase-associated protein 2, PRPP synthase-associated protein 2, 41 kDa phosphoribosypyrophosphate synthetase-associated protein, PRPSAP2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The PRPSAP2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMFCVTPP ELETKMNITK GGLVLFSANS NSSCMELSKK IAERLGVEMG KVQVYQEPNR ETRVQIQESV RGKDVFIIQT VSKDVNTTIM ELLIMVYACK TSCAKSIIGV IPYFPYSKQC KMRKRGSIVS KLLASMMCKA GLTHLITMDL HQKEIQGFFN IPVDNLRASP FLLQYIQEEI PDYRNAVIVA KSPASAKRAQ SFAERLRLGI AVIHGEAQDA ESDLVDGRHS PPMVRSVAAI HPSLEIPMLI PKEKPPITVV GDVGGRIAII VDDIIDDVDS FLAAAETLKE RGAYKIFVMA THGLLSSDAP RRIEESAIDE VVVTNTIPHE VQKLQCPKIK TVDISMILSE AIRRIHNGES MSYLFRNIGL DD |
Phosphoribosyl Pyrophosphate Synthetase-Associated Protein 2 (PRPSAP2) is a protein which relates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine, pyrimidine, histidine, tryptophan and NAD. PRS is a complex with 2 catalytic subunits and 2 associated subunits. PRPSAP2 encodes a non-catalytic associated subunit of PRS.
PRPSAP2 Human Recombinant produced in E. coli is a single polypeptide chain containing 392 amino acids (1-369) and having a molecular mass of 43.3kDa. PRPSAP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. |
| NCBI Summary: | This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| UniProt Code: | O60256 |
| NCBI GenInfo Identifier: | 4506133 |
| NCBI Gene ID: | 5636 |
| NCBI Accession: | NP_002758 |
| UniProt Related Accession: | O60256 |
| Molecular Weight: | 31kDa; 35kDa; 36kDa; 40kDa |
| NCBI Full Name: | phosphoribosyl pyrophosphate synthase-associated protein 2 isoform 1 |
| NCBI Synonym Full Names: | phosphoribosyl pyrophosphate synthetase associated protein 2 |
| NCBI Official Symbol: | PRPSAP2�� |
| NCBI Official Synonym Symbols: | PAP41�� |
| NCBI Protein Information: | phosphoribosyl pyrophosphate synthase-associated protein 2 |
| UniProt Protein Name: | Phosphoribosyl pyrophosphate synthase-associated protein 2 |
| UniProt Synonym Protein Names: | 41 kDa phosphoribosypyrophosphate synthetase-associated protein; PAP41 |
| Protein Family: | Phosphoribosyl pyrophosphate synthase-associated protein |
| UniProt Gene Name: | PRPSAP2�� |
