Description
| Product Name: | Human PFDN2 Recombinant Protein |
| Product Code: | RPPB4229 |
| Size: | 10µg |
| Species: | Human |
| Target: | PFDN2 |
| Synonyms: | Prefoldin subunit 2, PFDN2, PFD2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PFDN2 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 1mM DTT and 50mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAENSGRAGK SSGSGAGKGA VSAEQVIAGF NRLRQEQRGL ASKAAELEME LNEHSLVIDT LKEVDETRKC YRMVGGVLVE RTVKEVLPAL ENNKEQIQKI IETLTQQLQA KGKELNEFRE KHNIRLMGED EKPAAKENSE GAGAKASSAG VLVS |
Prefoldin subunit 2 (PFDN2) belongs to the prefoldin beta subunit family. The PFDN2 protein is one of 6 subunits of prefoldin, which is a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thus allowing them to fold correctly. PFDN2 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFDN2 also binds to a nascent polypeptide chain and promotes folding in an setting in which there are many competing pathways for nonnative proteins.
PFDN2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 174 amino acids (1-154 a.a.) and having a molecular mass of 18.8kDa. The PFDN2 is purified by proprietary chromatographic techniques.
| NCBI Summary: | This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UHV9 |
| NCBI GenInfo Identifier: | 15214669 |
| NCBI Gene ID: | 5202 |
| NCBI Accession: | BC012464 |
| UniProt Secondary Accession: | Q9UHV9,Q9P0P7, Q9UN05, |
| UniProt Related Accession: | Q9UHV9 |
| Molecular Weight: | 16,648 Da |
| NCBI Full Name: | Homo sapiens prefoldin subunit 2, mRNA |
| NCBI Synonym Full Names: | prefoldin subunit 2 |
| NCBI Official Symbol: | PFDN2�� |
| NCBI Official Synonym Symbols: | PFD2�� |
| NCBI Protein Information: | prefoldin subunit 2 |
| UniProt Protein Name: | |
| UniProt Gene Name: |
