Description
| Product Name: | Human PCID2 Recombinant Protein |
| Product Code: | RPPB4197 |
| Size: | 20µg |
| Species: | Human |
| Target: | PCID2 |
| Synonyms: | PCI Domain Containing 2, CSN12-Like Protein, PCIDomain-Containing Protein 2, F10, PCI domain-containing protein 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PCID2 protein solution (1.0 mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAYKCQTVIV QSFLRAFQAH KEENWALPVM YAVALDLRVF ANNADQQLVK KGKSKVGDMLEKAAELLMSC FRVCASDTRA GIEDSKKWGM LFLVNQLFKI YFKINKLHLC KPLIRAIDSS NLKDDYSTAQRVTYKYYVGR KAMFDSDFKQ AEEYLSFAFEHCHRSSQKNK RMILIYLLPV KMLLGHMPTV ELLKKYHLMQ FAEVTRAVSEGNLLLLHEAL AKHEAFFIRC GIFLILEKLK IITYRNLFKK VYLLLKTHQL SLDAFLVALK FMQVEDVDIDEVQCILANLI YMGHVKGYIS HQHQKLVVSK QNPFPPLSTV C |
PCIDomain Containing 2 (PCID2) is expressed in immature and early-stage Blymphocytes and regulates the expression of mitotic checkpoint protein MAD2. PCID2is a component of the TREX-2 complex, transcription and export complex 2, thiscomplex functions in docking export-competent ribonucleoprotein particles(mRNPs) to the nuclear entrance of the nuclear pore complex, nuclear basket.
PCID2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 341 amino acids (80-399 a.a) andhaving a molecular mass of 39.3kDa.PCID2 is fused to a 21 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the TREX-2 complex (transcription and export complex 2), which regulates mRNA export from the nucleus. This protein regulates expression of Mad2 mitotic arrest deficient-like 1, a cell division checkpoint protein. This protein also interacts with and stabilizes Brca2 (breast cancer 2) protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q5JVF3 |
| NCBI GenInfo Identifier: | 16741617 |
| NCBI Gene ID: | 55795 |
| NCBI Accession: | BC016614 |
| UniProt Secondary Accession: | Q5JVF3,Q3ZCX1, Q5TC57, Q5TC58, Q9H7K1, Q9HBZ7, Q9NUK6 Q9NVY1, Q9NW44, Q9NWH3 |
| UniProt Related Accession: | Q5JVF3 |
| Molecular Weight: | 52,100 Da |
| NCBI Full Name: | Homo sapiens PCI domain containing 2, mRNA |
| NCBI Synonym Full Names: | PCI domain containing 2 |
| NCBI Official Symbol: | PCID2�� |
| NCBI Official Synonym Symbols: | F10�� |
| NCBI Protein Information: | PCI domain-containing protein 2 |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | PCI domain-containing protein |
| UniProt Gene Name: | |
| UniProt Entry Name: |
