Description
| Product Name: | Human NUDT4 Recombinant Protein |
| Product Code: | RPPB2044 |
| Size: | 10µg |
| Species: | Human |
| Target: | NUDT4 |
| Synonyms: | Diphosphoinositol polyphosphate phosphohydrolase 2, DIPP-2, EC 3.6.1.52, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2, Nucleoside diphosphate-linked moiety X motif 4, NUDT4, DIPP2, KIAA0487, HDCMB47P, DIPP2beta, DIPP2alpha. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | NUDT4 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMMKFKPN QTRTYDREGF KKRAACLCFR SEQEDEVLLV SSSRYPDQWI VPGGGMEPEE EPGGAAVREV YEEAGVKGKL GRLLGIFENQ DRKHRTYVYV LTVTEILEDW EDSVNIGRKR EWFKVEDAIK VLQCHKPVHA EYLEKLKLGC SPANGNSTVP SLPDNNALFV TAAQTSGLPS SVR |
| UniProt Code: | Q9NZJ9 |
Nudix Type Motif 4 (NUDT4) regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates exemplifies a molecular switching activity with significant regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may be a factor in regulating intracellular trafficking.
NUDT4 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (1-180 a.a) and having a molecular mass of 22.7kDa. NUDT4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
