Description
| Product Name: | Human NIP7 Recombinant Protein |
| Product Code: | RPPB4097 |
| Size: | 25µg |
| Species: | Human |
| Target: | NIP7 |
| Synonyms: | Nuclear Import 7 Homolog, 60S ribosome subunit biogenesis protein NIP7 homolog KD93, CGI-37, HSPC031, FLJ10296, NIP7. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The NIP7 protein solution contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MRPLTEEETR VMFEKIAKYI GENLQLLVDR PDGTYCFRLH NDRVYYVSEK IMKLAANISG DKLVSLGTCFGKFTKTHKFR LHVTALDYLA PYAKYKVWIK PGAEQSFLYG NHVLKSGLGR ITENTSQYQG VVVYSMADIPLGFGVAAKST QDCRKVDPMA IVVFHQADIG EYVRHEETLT LEHHHHHH |
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) belongs to NIP7 family and contains 1 PUA domain. NIP7 interacts with pre-ribosome complex and may bind to RNA. NIP7 is vital for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
NIP7 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids (1-180 a.a.) and having a molecular mass of 21.5kDa.NIP7 is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NIP7: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. Belongs to the NIP7 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; RNA-binding Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function:protein binding |
| UniProt Code: | Q9Y221 |
| NCBI GenInfo Identifier: | 56404676 |
| NCBI Gene ID: | 51388 |
| NCBI Accession: | Q9Y221.1 |
| UniProt Secondary Accession: | Q9Y221,Q9NZZ0, B2RD04, |
| UniProt Related Accession: | Q9Y221 |
| Molecular Weight: | 15,222 Da |
| NCBI Full Name: | 60S ribosome subunit biogenesis protein NIP7 homolog |
| NCBI Synonym Full Names: | NIP7, nucleolar pre-rRNA processing protein |
| NCBI Official Symbol: | NIP7�� |
| NCBI Official Synonym Symbols: | KD93; CGI-37; HSPC031�� |
| NCBI Protein Information: | 60S ribosome subunit biogenesis protein NIP7 homolog |
| UniProt Protein Name: | 60S ribosome subunit biogenesis protein NIP7 homolog |
| UniProt Synonym Protein Names: | KD93 |
| Protein Family: | 60S ribosome subunit biogenesis protein |
| UniProt Gene Name: | NIP7�� |
| UniProt Entry Name: | NIP7_HUMAN |
